Postprandial Lipemia and Coronary Artery Disease: A significant risk factor

The role of high plasına total cholesterol and LDLcholesterol !eve! is well established in the process of atherosclerosis but this is not the same for triglycerides. The main lipids that acc uınulate in plasma in the postprandial state are triglyceride-rich lipoproteins_ Postprandial state is about 3/4 of a day and important interactions between lipoproteins occur at this time. Triglyceride-rich lipoproteins are chylomicrons, VLD and remmants of these lipids. Postprandial lipemia period involves the period during which the metabolism of these lipoproteins occur. It has been more than 40 years, since extensive research began on the role of these lipoproteins in the atherogenesis process. The data obtained from these studies show that postprandial lipids are associated with atheroma deposition and coronary events. Theoretically, in the presence of an erroneous metabolism of these lipids, the latter can i ntcracı with the vessel wall more closely and promote atherogenesis. They have close interactions with other lipoproteins and HDL, and they can directly promote atherogenesis by penetrating the arterial wall. Despite significant amount of knowledge obtained in this fie ld, further research is needed to belter elucidate the existing relationship between dietary intake, postprandial response and pathological events.