Hemodinamik öneme sahip mitral yetersizliğinin (MY) sol atriumu (SA) trombiis (TR) oluşumuna karşt komyucu etkisi yeterince IJilinnıektedir. Buna karştltk parava/viiler (PV) MY ile mitral protez kapak (MPK) fizerinde TR oluşumu arasmdaki etkileşme/er araşt/1'1/manıtşttr. Çahşmanıtz MPKTR bulunan olgulardaki klinik ve ekokardiyografik karakteristikleri araşttrnıayt ve parava/viiler MY (ortali/ eri) varltğ111111 MPK fizerinde TR oluşumwıu önleyici etkisinin bulunup bulunmadtğtm belirlemeyi anıaçlamaktadtr. Çalişma grubu MPK takibi için transtorasik ve transözofagea/ ekokardiyografi (TTE, TEE) uygu/annuş olan 265 (K/43, E/22, yaş ort. 43.4±24.9 ytl) hastadan oluşnıaktadtr. Ka/b ritmi 157 olguda (%59.2 ) at ri al fibri/ asyon (AF), diğerlerinde ise sinusal ritmdi. Mitral protez kapak TR, PVMY(>2), SATR ve spantan eko kontrasi (SEK) IJultmma stkltğt sn'OStyla 43 (%16.3), 22 (%8.3), 28 (%10.6) ve 98 (%37) olarak belirlendi. Mitral protez kapakta TR bulunan ve bulunmayan olgular arasmda yaş, cins . mitral kapak replasmanmdan TEE işlemine dek geçen siire , mekanik kapak tipi, ritm, sol atrium çapt (SAç), sol atrium appendiks (SAA) fraksiyonel alan değişimi (% FAD), SAA zirve g iriş ve çtktş aktm htzlan hakmundan anlanılt fark IJulunnıadt (p>0.05).Buna karştltk MPKTR bulunan olgularda, bulunmayanlara ktyas/a IJioprotez kapak (0 ve %15.3, pAnahtar Kelimeler: Parava/viiler mitral yetersizliği, mitral protez kapak, trombüs, transözozfageal ekokardiyografi

Protective effect of a significant mitral regurgitation (MR) from thrombus (THR) formatian in the le ft atrium (LA) is well documented. But inte raction between paravalvular (PV) MR and THR formation on presthetic mitral valves (PMY) has not been investigated. The aim of this study was to investigate the elinical and echocardiographic characteristics of patients with PMYTHR, and to assess whether or not PVMR protects PMY agai nts THR. Study population coınprised 265 patients (F 143, M 122, mean age 43.4±24.9) who underwent transthoracic and transesophageal echocardiography (TTE, TEE) for the follow- up of PMY evaluation. Atrial fibrillation (AF) was present in 157 patients (59.%). Presthetic valve THR, PVMR (~2), LATHR and spontaneous echo contrast (SEC) were diagnosed in 43 (16.3%), 22 (8.3%), 28 (l 0.6%) and 98 (37%) patients, respectively. Age, gender, duration between valve replacement and TEE, mechanical valve types, rhythm, diameter of LA, fractional area change of LA appendage (LAA), inward and outward velocities of LAA were not found to be significantly different between patients with and without PMYTHR (group A and B), respectively (p>0.05). However, frequency of biTiirk Kardiyol Dem Arş 1999; 27:384-388 oprosthetic valve (0 vs 15.3%, pKeywords: Mitral regurgitation, presthetic valve, thronıbus