. 2013; 41(2): 113-114 | DOI: 10.5543/tkda.2013.08504 | |||
Beta-bloker çagında kalp yetersizliği prognozunun belirlenmesinde egzersiz testi: Zamana meydan okumakMarc Simon, Özlem SoranDeparment of Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, United StatesStanding the test of time: exercise testing for heart failure prognosis in the beta-blocker eraMarc Simon, Özlem SoranDeparment of Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, United StatesHeart failure is a major world health problem. Despite many treatments, mortality and hospitalizations remain high. Prognosis can be quite difficult, particularly regarding the interaction of multiple therapies on our diagnostic tools. Therefore, it is imperative that we periodically revisit the utility of prognostic markers to ensure that that our interpretation of testing results remain clinically relevant. Cardiopulmonary exercise testing is a prime example of this conundrum. Originally popularized for the prediction of outcomes in systolic heart failure prior to the beta-blocker era, it remains widely utilized particularly in assessing severity of heart failure in patients considered for heart transplant. Since this time, beta-blockers have been shown to significantly improve outcomes in heart failure, as have other treatments including angiotensin receptor blockers, aldosterone receptor blockers, implantable defibrillators for primary prevention of sudden death, and cardiac resynchronization devices. Marc Simon, Özlem Soran. Standing the test of time: exercise testing for heart failure prognosis in the beta-blocker era. . 2013; 41(2): 113-114 Sorumlu Yazar: Marc Simon, United States |
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