. 2024; 21(2): 0-0 | |||
Potential Hepatoprotective Effects of Irbesartan, an Accessible Angiotensin II Receptor Blocker, Against Cisplatin-Induced Liver Injury in a Rat ModelOnur Ertunc1, Yalçın Erzurumlu2, Mehtap Savran3, Deniz Catakli3, Eltaf Doğan Kıran4, Şakir PEKGÖZ51Department Of Pathology, Faculty Of Medicine, Suleyman Demirel University, Isparta, Turkey2Department of Biochemistry, Faculty of Pharmacy, Suleyman Demirel University, Isparta, Turkey 3Department Of Pharmacology, Faculty Of Medicine, Suleyman Demirel University, Isparta, Turkey 4Department of Biochemistry, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey 5Department of Pathology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey INTRODUCTION: Drug-induced liver injury is a common adverse reaction that frequently occurs with chemotherapeutic agents, such as cisplatin (CIS). The present study seeks to enhance our comprehension of drug actions and their associated adverse effects by examining the toxicity of cisplatin on rat liver tissue. Basically, we aim to investigate the potential hepatoprotective effects of irbesartan (IRB), an easily accessible angiotensin II receptor blocker, in mitigating the hepatotoxicity induced by cisplatin. Onur Ertunc, Yalçın Erzurumlu, Mehtap Savran, Deniz Catakli, Eltaf Doğan Kıran, Şakir PEKGÖZ. Potential Hepatoprotective Effects of Irbesartan, an Accessible Angiotensin II Receptor Blocker, Against Cisplatin-Induced Liver Injury in a Rat Model. . 2024; 21(2): 0-0 Corresponding Author: Onur Ertunc, Türkiye |
|