HEMORRHAGIC CORPUS LUTEUM: CLINICAL MANAGEMENT UPDATE (review of literature)Mykhailo V Medvediev1, Antonio Malvasi2, Sarah Gustapane3, Andrea Tinelli41Dnipropetrovsk Medical Academy Of Health Ministry Of Ukraine 2Department Of Obstetrics And Gynaecology, Gvm Care & Research, Santa Maria Hospital, Bari, Italy 3Department of Obstetrics and Gynecology, “Veris delli Ponti” Hospital, Scorrano, Lecce, Italy 4Chief of Department of Obstetrics and Gynecology, “Veris delli Ponti” Hospital, Scorrano, Lecce, Italy
Background: Hemorrhagic corpus luteum (HCL) is an ovarian cyst formed after ovulation and caused by spontaneous bleeding into a corpus luteum (CL) cyst. When HCL rupture happens, a hemoperitoneum results. Clinical symptoms are mainly due to peritoneal irritation by the blood effusion. The differential diagnosis is extensive and standard management is not defined. Aim of the study: authors elaborated a comparison of differential diagnosis and therapeutic modalities from laparoscopic approach to nonsurgical, medical options, since hemorrhage from HCL is often self-limiting. Material & Methods: authors reviewed all data implicated with the development of HCL, trying to give homogeneity to literature data. Results: authors analyzed extensive literature data and subdivided the medical approach in many topics. Wait-and-see attitude avoids unnecessary laparoscopic surgery using supportive therapies (antifibrinolytic, analgesics, liquid infusion, transfusions and antibiotic prophylaxis). Surgical therapy: the operative management should be laparoscopic, with surgical options like luteumectomy, ovarian wedge-shaped excision or oophorectomy. Prevention: the possibility to preserve fertility is essential, mainly in patients with bleeding disorders or undergoing anticoagulant therapy; therefore, they need estro-progestinics or GnRH analogues to prevent ovulation and avoid further episodes of HCL. Conclusion: This review will aid physicians to make an early diagnosis of HCL, to avoid unnecessary surgery and use the most effective treatment. Keywords: Corpus luteum, ovarian cyst, ectopic pregnancy, laparoscopy
Mykhailo V Medvediev, Antonio Malvasi, Sarah Gustapane, Andrea Tinelli. HEMORRHAGIC CORPUS LUTEUM: CLINICAL MANAGEMENT UPDATE (review of literature). TJO. 2020; 17(4): 0-0
Corresponding Author: Mykhailo V Medvediev, Ukraine |
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