Virilizing Adrenocortical Carsinoma Oncocytic Variant in a Child with Heterosexual Precocious Puberty and Literatüre Rewiev

Introduction
Adrenocortical carcinoma (ACC) are categorized as functional (hormone-secreting), which is most commonly found in children and adolescents, or non-functional (silent), which is usually found in adults with symptoms of abdominal discomfort or back pain caused by the large mass of the tumor
Material Method
Here, we describe a rare case of a 4year-old girl with pure androgen secreting adrenal oncocytic carsinoma who presented with premature pubarche, clitoromegaly and advanced bone maturation.
Results
we diagnosed adrenal carsinoma in patient who presented with signs of peripheral puberty precoccus
Discussion
To the best of our knowledge, only one functional oncocytic adrenocortical carcinoma has been reported in the literature in pediatric age population. So this case we have reported is the second case in the literature.
Conculision
In conclusion, virilization is an important manifestation of adrenocortical tumors in both sexes. We report the first case of virilizing functional oncocytic adrenocortical carsinoma in a girl with accelerated skeletal maturation, clitoromegaly and premature pubarche. A high index of suspicion and an increased awareness of pediatricians play an important role in the early diagnosis and treatment of this disease.