. 2015; 23(3): 90-97 | |||
In Vivo Anticancer Activities of Vanillin Thiosemicarbazone Complexes with Co(II) and Ni(II)Sha M. S. Shahriar, S. M.M. Ali, M. JesminDepartment Of Applied Chemistry And Chemical Engineering, University Of Rajshahi, Rajshahi-6205, Bangladesh.The anticancer activities of vanillin thiosemicarbazone complexes with Co(II) and Ni(II) have been studied against Ehrlich ascites carcinoma (EAC) cells in Swiss albino mice. Both the complexes were administrated into the intraperitoneal cavity of the EAC-inoculated mice at two doses (5 and 7.5 mg/kg i.p.). The anticancer activities were studied by monitoring the parameters such as cell growth inhibition, tumor weight measurement, survival time of EAC-bearing mice, as well as the changes in depleted hematological parameters due to tumorigenesis. All data were compared with those of a known Sha M. S. Shahriar, S. M.M. Ali, M. Jesmin. In Vivo Anticancer Activities of Vanillin Thiosemicarbazone Complexes with Co(II) and Ni(II). . 2015; 23(3): 90-97 Sorumlu Yazar: Sha M. S. Shahriar, Bangladesh |
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