Phytochemical and Biological Studies of Butea Frondosa Roxb. Leaves Growing in Egypt
Nagwa M. Ammar1, Mohammed S. Hefnawy2, Doha A. Mohamed3, Nabil E. Khamis4, Ahmed H. Afifi1, Tom J. Mabry51Pharmacognosy Department, National Research Centre, Dokki, Cairo,Egypt.2Pharmacognosy Department, Faculty of Pharmacy, Cairo Univeristy, Egypt.
3Food Sciences and Nutrition Department, National Research Centre, Dokki, Cairo, Egypt.
4Tanning Materials and Protein Chemistry Department, National Research Centre, Dokki, Cairo,Egypt.
5Molecular Cell and DevelopmentalBiology,The Schoolof Biological Science Department, Texas University, USA.
This study aimed to the discovery of new biologically active natural products with hormonelike activity from Butea frondosa Roxb., Family Leguminosae growing in Egypt. The investigation of estrogenlike activity showed that both the successive non-polar and methanolic extracts showed a significant estrogen-like activity in immature female rats. GLC analysis the non-polar bioactive revealed the presence of eicosane (22.5%) and -amyrin (20.5%) as the major components in the unsaponifiable matter, while palmitic (24.9%) and linoleic (36.8%) acids were the main saturated and unsaturated fatty acids. The successive bioactive methanolic extract was subjected to chromatographic separation to yield five flavonoids identified as vicenin II, vitexin, chrysoeriol 7-o--D-glucuronic acid, 6,8-di-C-rhamnosyl apigenin and luteolin.
Keywords: butea frondosa, estrogenic like activity, bioactive compoundsSorumlu Yazar: Doha A. Mohamed, Egypt
| ARAÇLAR |
 Tam Metin PDF Yazdır Alıntıyı İndir RIS EndNote BibTex Medlars Procite Reference Manager E-Postala Paylaş Yazara e-posta gönder
Benzer makaleler Google Scholar |