A Comparative Histopathological Investigation of The Effect of Lyophilized Amniotic Membrane on Wound Healing as An Allograft Material in Rats
Rukiye Güler1, Necati Uran1, F. Hüsniye Dilek21From Department of Oral Surgery, Faculty of Dentistry, Hacettepe University, Ankara, Türkiye.2From Department of Pathology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.
This study, performed on 40 rats, has been carried out to evaluate the wound healing effect of lyophilized amniotic membrane, which is a biological material.
Full thickness wounds were produced on the dorsal regions of rats. The membrane was applied to one half of the experimental population whereas the other group was left uncovered. The histopathological effect of the membrane on the wound surfaces was examined following biopsies taken from the wound sites on the 7, 14, 21 28th day. The study has shown both microscopically and histopathologically that the graft has an accelerating effect on epithelization and that the membrane is biodegradable.
Rukiye Güler, Necati Uran, F. Hüsniye Dilek. A Comparative Histopathological Investigation of The Effect of Lyophilized Amniotic Membrane on Wound Healing as An Allograft Material in Rats. . 1993; 6(3): 209-219
Sorumlu Yazar: Rukiye Güler, Türkiye
Sorumlu Yazar: Rukiye Güler, Türkiye
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