Anti-Thyroid Effect of White Cabbage Glucosinolates

The glucosinolates of crushed seeds of white cabbage were left for hydrolysis in contact with some distilled water, and the hydrolysis products were extracted, concentrated, and administered aurally to rats in doses representing 1, 2 and 4 gm seeds/100 gm body weight/day at intervals of 10, 20 and 30 days. The hydrolysate of 4 gm seeds/100 gm body weight/day fed for 30 days caused marked decreases in serum T3 and T4 concentrations analogous with those resulted from methimazole treatment.