Comparison of the Analgesic Effects of Intravenous Dexketoprofen, Ibuprofen and Fentanyl in Patients Suffering from Renal Colic Pain in the Emergency Department

Aim: Renal colic is a urological emergency usually caused by urolithiasis and manifested by severe pain. Emergency treatment's main purpose is to effectively relieve pain and urinary obstruction without impaired renal function. We aimed to measure the efficacy and safety of intravenous (IV) ibuprofen on renal colic pain.
Materials and Methods: 235 patients who were admitted to the emergency department between 01.01.2016-30.06.2017 and were suspected of renal colic that scored at least 2 points on the Visual Analog Scale or FLACC scale were included in the study after obtaining detailed consent. 154 patients whose diagnoses were confirmed radiologically, included in the study as GroupA (dexketoprofen) (n=35), GroupB (ibuprofen400mg) (n=37), GroupC (ibuprofen800mg) (n=44), GroupD (fentanyl) (n=38). VAS and FLACC scales were re-evaluated on the 20th, 40th, and 60th minutes after drug administration.
Results: 64.9% of the patients were male and 35.1% were female, and the mean age was 42.31 (±15.46). It was observed that all 4 of the medications given to patients who applied to the emergency department with flank pain provided effective analgesia, but the drugs could not establish a statistically significant advantage over each other.
Conclusion: İntravenous administration of ibuprofen is considered to be an effective and safe alternative in the treatment of renal colic pain in the emergency department.