Levels of Total Platelet Mass in Patients Admitted to Emergency Department and Diagnosed with Obstructive Sleep Apnea Syndrome

Objective: The objective of this study was to investigate whether there was a relationship between the levels of platelet mass index and OSAS and to compare biochemical parameters among comorbidity groups among OSAS patients.
Material & Methods: The patients were divided into two groups; patient group consisted of patients who had previously presented to the emergency department of our hospital and were diagnosed with OSAS through polysomnography, while control group included individuals who had no diagnosed chronic disease.
The Patients in the OSAS group were further divided subgroups as diabetes, diabetes + hypertension, diabetes + hyperlipidemia, diabetes + cardiovascular disease, diabetes + hypertension + hyperlipidemia, hyperlipidemia, cardiovascular disease and hypertension.
Physical examination, complete blood count and biochemical test outcomes of both groups, and polysomnography data of the patient group were retrospectively evaluated.
Results: The mean BMI value was statistically significantly higher in OSAS patients compared to the control group (24.28±1.00 vs 29.73±2.51 Kg/m2). The mean platelet volume (MPV) was significantly higher in the control group (10.13±1.09) compared to the OSAS group (7.98±1.32) (p<0.001). Total platelet mass indeks found with multiplying platelet counts and MPV was significantly higher in the control group (2,737.92±548.90) compared to the OSAS patients (2,104.89±462.86) (p<0.001).
Conclusion: According to the results of this study platelet mass index, MPV and/or total platelet count is not diagnostic. Especially in patients presenting to emergency department with the complaints of fatigue, headache, inattention and daytime drowsiness; however may be a warning parameter idicating that it might be OSAS.