Anatol J Cardiol. 2022; 26(6): 460-465 | DOI: 10.5152/AnatolJCardiol.2022.1324 | |||
Molecular Approach of Hereditary Arrhythmias, Long QT Syndrome, and Arrhythmogenic Right Ventricular CardiomyopathyHanife Saat1, Ibrahim Şahin1, Haktan Bagğış Erdem2, Senem Özgür3, Semiha Terlemez Tokgöz4, Taha Bahsi&775;21Department of Medical Genetics, University of Health Sciences, Dışkapı Yıldırım Beyazıt Research and Training Hospital, Ankara, Turkey2Department of Medical Genetics, University of Health Sciences, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey 3Department of Pediatric Cardiology, Dr. Sami Ulus Maternity, Children's Health and Diseases Training and Research Hospital, Ankara, Turkey 4Department of Pediatric Cardiology, Faculty of Medicine, Gazi University, Ankara, Turkey Background: Hereditary cardiac arrhythmias result from mutations in various genes encoding ion channels. One major channelopathy is long QT syndrome, which has excel-lent genetic and clinical heterogeneity. Arrhythmogenic right ventricular cardiomyopathy, another hereditary arrhythmia type, also shows high genetic heterogeneity and variable expressivity. Next-generation sequencing is an effective tool to reveal the dis-ease’s underlying genetic etiology. Hanife Saat, Ibrahim Şahin, Haktan Bagğış Erdem, Senem Özgür, Semiha Terlemez Tokgöz, Taha Bahsi&775;. Molecular Approach of Hereditary Arrhythmias, Long QT Syndrome, and Arrhythmogenic Right Ventricular Cardiomyopathy. Anatol J Cardiol. 2022; 26(6): 460-465 Corresponding Author: Hanife Saat |
|