Anatol J Cardiol. 2015; 15(1): 8-12 | DOI: 10.5152/akd.2014.5135 | |||
C771G (His241Gln) Polymorphism of MLXIPL Gene, TG levels and coronary artery disease: A case control studyAsghar Ghasemi1, Hasan Aghajani2, Soudabeh Fallah1, Mehrdad Assadi3, Morteza Seifi41Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran-Iran2Department of Heart Center, Faculty of Medicine, Tehran University of Medical Sciences, Tehran-Iran 3Department of Medical Mycology and Parasitology, Faculty of Public Health, Tehran University of Medical Sciences, Tehran-Iran 4Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran-Iran; Department of Medical Genetics, University of Alberta, Edmonton, AB-Canada. Objective: It is suggested that C771G (His241Gln) polymorphism of MLXIPL gene might be a genetic risk factor for coronary artery disease (CAD); therefore, the aim of the present study was to investigate the association between C771G polymorphism of MLXIPL gene and the pathogenesis of CAD in Iranian patients with coronary artery stenosis and control subjects. MLXIPL geninin C77IG (His241Gln) polimorfizminin TG seviyesi ve koroner arter hastalığı: Bir olgu kontrollü çalışmaAsghar Ghasemi1, Hasan Aghajani2, Soudabeh Fallah1, Mehrdad Assadi3, Morteza Seifi41Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran-Iran2Department of Heart Center, Faculty of Medicine, Tehran University of Medical Sciences, Tehran-Iran 3Department of Medical Mycology and Parasitology, Faculty of Public Health, Tehran University of Medical Sciences, Tehran-Iran 4Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran-Iran; Department of Medical Genetics, University of Alberta, Edmonton, AB-Canada. Amaç: MLXIPL geninin C771G (His 241 Gln) polimorfizminin koroner arter hastlığı (KAH) için genetik bir risk faktörü olabileceği ileri sürülüyor; bundan dolayı, sunulan çalışmanın amacı, İranlı koroner arter darlığı olan ve kontrol kişilerinde KAH patogenezi ile, MLXIPL genini C//G polimorfizmi ilişkisini araştırmaktadır. Asghar Ghasemi, Hasan Aghajani, Soudabeh Fallah, Mehrdad Assadi, Morteza Seifi. C771G (His241Gln) Polymorphism of MLXIPL Gene, TG levels and coronary artery disease: A case control study. Anatol J Cardiol. 2015; 15(1): 8-12 |
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