Clinical value of Leukocyte counts in evaluation of patients with suspected appendicitis in emergency departmentMohammad Zikrullah Tamanna1, Uzma Eram2, Turki Mohsen Al Harbi1, Saleh Awad Alrashdi1, Shafkat Ullah Khateeb1, Saleem Ahmed Aladhrain1, Abdul Muthalib Hussain31Emergency Departement, King Fahad Medical City, Riyadh, Saudia Arabia 2Department Of Community Medicine, J.n.medical Collage, A.m.u.aligarh, India 3Department Of Pulmonary And Critical Care Medicine, King Fahad Medical City,riyadh
Objectives: - The objective of this study was to assess the value of total leukocyte count in patients presenting to the emergency department (ED) with sign and symptoms suggestive of acute appendicitis. Methods: - Patient demographics, presenting sign, and symptoms, initials total leukocyte count and discharge diagnosis was documented retrospectively. Admitted patients were followed for surgical and clinical outcomes, and discharged patients followed up by telephonic interview. Results: -Out of 116 eligible patients 48 patients was found to have acute appendicitis. Total Leukocyte count ≥10,000cell/mm3 yielded a sensitivity of 89.58% and a specificity of 64.71%.The positive predictive value (PPV) was 64.18%, and the negative predictive value( NPV ) was 89.80%.The positive likelihood ratio( +LR) was 2.54, and the negative likelihood ration( –LR ) was 0.16. The area under the curve (AUC) for the receiver operating characteristic( ROC) curve was 0.822, which was moderately accurate.
Conclusions: -The total leukocyte counts are helpful in the diagnosis and exclusion of acute appendicitis. The elevated leukocyte count ≥10,000cells/mm3was statistically associated with the presence of acute appendicitis. The ROC curve suggests there is value of total leukocyte counts and has sufficient sensitivity and specificity to be clinical value in the diagnosis of acute appendicitis Keywords: appendicitis, leukocyte counts, abdominal pain
Mohammad Zikrullah Tamanna, Uzma Eram, Turki Mohsen Al Harbi, Saleh Awad Alrashdi, Shafkat Ullah Khateeb, Saleem Ahmed Aladhrain, Abdul Muthalib Hussain. Clinical value of Leukocyte counts in evaluation of patients with suspected appendicitis in emergency department. . 2012; 18(6): 474-478
Corresponding Author: Mohammad Zikrullah Tamanna, Saudi Arabia |
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